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Eosinophilic cellulitis: five cases.

R Lindskov1, N Illum, K Weismann

  • 1Department of Dermatology, Rigshospitalet, University of Copenhagen, Denmark.

Acta Dermato-Venereologica
|January 1, 1988
PubMed
Summary
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Eosinophilic cellulitis (Wells' syndrome) can affect young children, presenting with unusual scalp lesions and necrotizing granulomas. Early diagnosis and steroid therapy are crucial for managing this rare condition.

Area of Science:

  • Dermatology
  • Pediatric Dermatology
  • Pathology

Background:

  • Eosinophilic cellulitis, also known as Wells' syndrome, is a rare inflammatory skin condition.
  • Previous reports have included limited pediatric cases.

Observation:

  • This study details five cases of eosinophilic cellulitis.
  • Four out of five patients were under 10 years old, with one as young as 20 months.
  • One child presented with unique hard, tender subcutaneous scalp swellings.

Findings:

  • Histological examination of the scalp lesions revealed extensive subcutaneous necrotizing granulomas.
  • These specific granulomatous lesions have not been previously associated with eosinophilic cellulitis.
  • The condition often shows a positive response to corticosteroid treatment.

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Implications:

  • Highlights the potential for eosinophilic cellulitis to occur in very young children.
  • Emphasizes the importance of recognizing rare clinical and histological presentations.
  • Underscores the need for clinicians and pathologists to be familiar with Wells' syndrome for timely and effective steroid therapy.