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Hemiballismus: changes in cerebrospinal fluid
V Kostic1, B Djuricic, W Paschen
1Department of Neurology, School of Medicine, Belgrade, Yugoslavia.
Acta Neurologica Scandinavica
|August 1, 1988
Abstract:
Concentrations of serotonin metabolite, 5-hydroxyindoleacetic acid (5-HIAA), and dopamine metabolites, homovanillic acid (HVA) and 3,4-dihydroxy-phenylacetic acid (DOPAC), were measured in the samples of cerebrospinal fluid of 5 patients with acute hemiballismus. The only significant change was the increased content of HVA compared to controls. This finding support the hypothesis on the increased dopamine turnover in hemiballismus and provide a rational basis for the present treatment with antidopaminergic agents.