Related Experiment Video
Updated: May 2, 2026

Sequential Application of Glass Coverslips to Assess the Compressive Stiffness of the Mouse Lens: Strain and Morphometric Analyses
Published on: May 3, 2016
Developmental changes in accommodation evidenced by an ultrabiomicroscopy procedure in patients of different ages
Giovanna Benozzi1, Juliana Leiro2, Sonia Facal2
1Centro de Investigación Avanzada para la Presbicia (C.I.A.P.) . Ciudad Autónoma de Buenos Aires, Republic of Argentina. ; Pharmacology Unit, School of Dentistry, Buenos Aires University. Ciudad Autónoma de Buenos Aires, Republic of Argentina.
Abstract:
We demonstrate that changes in the behaviour of the contractile ciliary muscle accompanied by augmented rigidity of the lens are the most important aspects in the loss of accommodation. With ultrabiomicroscopy (UBM), we demonstrated that the performance of the ciliary muscle is diminished and accompanied by rigidity of the lens. Both lens thickness and trabecular-ciliary process distance (TCPD) were the parameters that showed major alterations with the loss of accommodation in patients of different ages. The results indicated that the differences between these parameters in farsightedness and nearsightedness in the different groups of patients were positively correlated.

