Pyogenic granuloma in a 5-month-old treated with topical timolol

Area of Science:

• Dermatology
• Pediatric Dermatology
• Pharmacology

Background:

• Pyogenic granulomas are common benign vascular tumors, frequently occurring in infants and children.
• Traditional treatments include surgical excision, laser therapy, and cryotherapy, which can lead to scarring or discomfort.

Observation:

• A 5-month-old infant presented with a pyogenic granuloma on the cheek.
• The lesion was treated with a topical 0.5% gel-forming solution of timolol.

Findings:

• Complete regression of the pyogenic granuloma was observed after 1 month of topical timolol treatment.
• No recurrence of the lesion was noted at an 8-month follow-up, indicating sustained efficacy.

Implications:

• Topical timolol presents a promising, non-invasive therapeutic option for pediatric pyogenic granulomas.
• This approach may be particularly beneficial in cases where scarring is a concern or other treatments are contraindicated.