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Many drugs contain unique scaffolds with varying structural relationships to scaffolds of currently available

Ye Hu1, Jürgen Bajorath1

  • 1Department of Life Science Informatics, B-IT, LIMES, Program Unit Medicinal Chemistry and Chemical Biology, Rheinische Friedrich-Wilhelms-Universität Bonn, Dahlmannstr. 2, D-53113 Bonn, Germany.

European Journal of Medicinal Chemistry
|March 8, 2014
PubMed

Keywords:
Approved drugsBioactive compoundsDrug-unique scaffoldsMatched molecular pairsScaffoldsSubstructure relationshipsTopological equivalence

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