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Does ozone autohemotherapy have positive effect on neurologic recovery in spontaneous spinal epidural hematoma?

Lei Yu1, Xiaojie Lu1, Huachao Shi1

  • 1Department of Neurosurgery, Nanjing Medical University affiliated Wuxi No. 2 People's Hospital, Wuxi, Jiangsu, China.

The American Journal of Emergency Medicine
|March 8, 2014
PubMed
Abstract

No abstract available in PubMed .

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Secondary Spinal Cord Injury llI: Pathophysiology01:25

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Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
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