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The role of xerostomia in burning mouth syndrome: a case-control study
Luciana Alvarenga da Silva1, José Tadeu Tesseroli de Siqueira2, Manoel Jacobsen Teixeira3
1Departmento de Neurologia, Universidade de São Paulo, Sao PauloSP, Brazil, Postgraduation Student, Departmento de Neurologia, Universidade de São Paulo, Sao Paulo SP, Brazil;
Objective:
To assess the efficacy of anti-xerostomic topical medication (urea 10%) in patients with burning mouth syndrome (BMS).
Method:
Thirty-eight subjects diagnosed with BMS according to the International Association for the Study of Pain guidelines were randomized to either placebo (5% sodium carboxymethylcellulose, 0.15% methyl paraben, and 10% glycerol in distilled water qsp 100 g) or treatment (urea 10%) to be applied to the oral cavity 3-4 times per day for 3 months. The patients were evaluated before and after treatment with the following instruments: the EDOF-HC protocol (Orofacial Pain Clinic - Hospital das Clínicas), a xerostomia questionnaire, and quantitative sensory testing.
Results:
There were no differences in salivary flow or gustative, olfactory, or sensory thresholds (P>0.05). Fifteen (60%) patients reported improvement with the treatments (P=0.336).
Conclusion:
In conclusion, there were no differences between groups, and both exhibited an association between reported improvement and salivation.
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