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Published on: September 3, 2016
Does Staphylococcus aureus nasal carriage require eradication prior to elective ambulatory surgery in children?
Zvi Steiner1, Orna Ben Natan, Igor Sukhotnik
1Department of Pediatric Surgery B, Hillel Yaffe Medical Center, Hadera, Israel, tzvikast@012.net.il.
Insights
Staphylococcus aureus nasal carriage in children undergoing surgery did not correlate with wound infections. Routine screening for S. aureus nasal colonization may not be necessary for these pediatric patients.
Area of Science:
- Pediatric infectious diseases
- Surgical site infections
- Microbiology
Background:
- Rising rates of community-associated Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) in children.
- Need to understand the relationship between nasal carriage and infection risk.
Purpose of the Study:
- To investigate the rates of Staphylococcus aureus nasal colonization in children.
- To determine if there is a correlation between nasal carriage and subsequent wound infection.
Main Methods:
- Prospective study of 1,127 children undergoing elective day-care surgical procedures.
- Nasal swabs collected pre-operatively.
- Follow-up for wound infection 1-2 weeks post-surgery.
Main Results:
- 20.2% of children carried S. aureus in their nasal passages.
- MRSA nasal carriage was found in 0.62% of the children.
- No correlation was found between S. aureus nasal carriage and surgical wound infections; none of the five children with wound infections were nasal carriers.
Conclusions:
- Nasal S. aureus carriage does not appear to be a significant risk factor for wound infections in children undergoing elective ambulatory surgery.
- Screening for and eradicating S. aureus nasal colonization may not be clinically indicated in this pediatric population.
Purpose:
Rates of community-associated Staphylococcus aureus, and particularly of methicillin-resistant Staphylococcus aureus (MRSA) in children, have increased in recent years. We investigated rates of nasal colonization of S. aureus, and a possible correlation between nasal carriage and wound infection.
Methods:
A prospective study of children scheduled for elective day-care surgical procedures between January 2008 and December 2012 at one medical center. Nasal swabs were taken before surgery, and follow-up was performed 1-2 weeks following surgery.
Results:
Of 1,127 children (median age 2 years, 70.6% males), positive nasal swabs were detected in 228 (20.2%). Rates of S. aureus nasal carriage were lowest for ages 6 months to 2 years and highest for ages 4-11 years. Child's sex did not associate with the risk for positive nasal swabs. Positive nasal swabs for MRSA were detected in five boys (0.62% of the population). Five children (0.44%) had wound infection. None of them was a nasal carrier.
Conclusions:
No correlation was observed between positive nasal swabs and wound infection in children who were candidates for elective ambulatory operations. This suggests that evaluation of S. aureus nasal carriage and eradication may not be necessary in this population.
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