Tanzawaic acids I-L: Four new polyketides from Penicillium sp. IBWF104-06
Louis P Sandjo1, Eckhard Thines2, Till Opatz1
1Johannes-Gutenberg-University Mainz, Institute of Organic Chemistry, Duesbergweg 10-14, D-55128 Mainz, Germany.
Abstract:
Four new polyketides have been identified in culture filtrates of the fungal strain Penicillium sp. IBWF104-06 isolated from a soil sample. They are structurally based on the same trans-decalinpentanoic acid skeleton as tanzawaic acids A-H. One of the new compounds was found to inhibit the conidial germination in the rice blast fungus Magnaporthe oryzae at concentrations of 25 μg/mL.
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