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[Intraoperative margin evaluation in breast-conservation surgery using margin probe technique].

Idit Melnik1, Ilia Lifshitz1, Pioter Weinshtein1

  • 1Department of General and Vascular Surgery, Barzilai Medical Center, Ashkelon affiliated with the Faculty of Health Sciences, Ben-Gurion University of the Negev.

Harefuah
|March 11, 2014
PubMed
Summary
This summary is machine-generated.

The Margin Probe technique, an intraoperative tool, helps surgeons assess breast cancer margins during surgery. This method is safe and feasible, reducing the need for repeat operations in patients undergoing breast conservation surgery.

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Area of Science:

  • Oncology
  • Surgical Innovation
  • Medical Devices

Context:

  • Surgical margin involvement is a key prognostic factor in breast conservation surgery.
  • Positive margins necessitate re-operation, increasing patient burden and healthcare costs.
  • There is a clinical need for real-time tools to assess surgical margins intraoperatively.

Purpose:

  • To evaluate the feasibility and safety of the Margin Probe technique in assessing surgical margins during breast conservation surgery.
  • To determine the impact of the Margin Probe on the rate of re-operations due to positive margins.

Summary:

  • The Margin Probe technique utilizes radiofrequency signals and spectroscopy to analyze resected tissue for margin involvement.
  • In a study of 64 patients, 37.5% required intraoperative re-excision based on Margin Probe signals, with 37.5% of these confirmed positive by pathology.
  • The overall rate of second surgeries was 6.25%, with only one false negative result, indicating high accuracy.

Impact:

  • The Margin Probe technique is a feasible and safe tool for intraoperative margin assessment.
  • Implementation of the Margin Probe can significantly reduce the rate of repeat operations after breast conservation surgery.