[Soluble form of trigger receptor expressed on myeloid cells-1 as a marker of burn wound mixed infection]

Detection ofearly non-bacteriological markers ofburn wound mixed microbial infection.

The level of soluble form of trigger receptor expressed on myeloid cells-1 (sTREM-1) and cytokines in blood sera of 60 burn patients on days 3 - 6 and 10 - 17 after the burn was studied by solid phase enzyme immunoassay.

At the early periods of burn disease the level ofsTREM- 1 in sera may be a non-bacteriological marker of burn wound mixed infection: at days 3 - 6 after the injury - higher than 298.8 pg/ml, at days 10 - 17 after the burn - higher than 294.2 pg/ml.

Level of sTREM-1 in blood sera of patients with severe thermic injury could be proposed as an additional laboratory marker of burn wound mixed microbial infection.