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Updated: May 2, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
Published on: November 5, 2016
Biomedical applications of synthetic, biodegradable polymers for the development of anti-infective strategies
Serban Bertesteanu, Mariana Carmen Chifiriuc, Alexandru Mihai Grumezescu
1University of Bucharest, Faculty of Biology, Microbiology Department, Ale. Portocalelor 1-3, 60101, Bucharest, Romania. carmen_balotescu@yahoo.com.
Abstract:
The emergence of antibiotic resistance in microbial strains is representing one of the major threats to public health worldwide, due to the decreased or total cancelling of the available antibiotics effectiveness, correlated with the slow development of novel antibiotics. Due to their excellent biodegradability and biocompatibility, the synthetic polymers could find a lot of biomedical applications, such as the development of biomaterials with optimized properties and of drug delivery systems. This review is focusing on the applications of synthetic, biodegradable polymers for the improvement of antiinfective therapeutic and prophylactic agents (i.e., antimicrobial and anti-inflammatory agents and vaccines) activity, as well as for the design of biomaterials with increased biocompatibility and resistance to microbial colonization.
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