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STINGRAY: system for integrated genomic resources and analysis.

Glauber Wagner, Rodrigo Jardim, Diogo A Tschoeke

  • 1Laboratório de Biologia Computacional e Sistemas, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (FIOCRUZ), Avenida Brasil 4365, 21040-360 Rio de Janeiro, Rio de Janeiro, Brazil. davila@fiocruz.br.

BMC Research Notes
|March 11, 2014
PubMed
Summary
This summary is machine-generated.

The STINGRAY system simplifies genomic and expression data analysis from Sanger and Next Generation Sequencing (NGS) platforms. This bioinformatics tool offers an integrated workflow, database, and user-friendly interface for efficient data management and annotation.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Genomic and expression data analysis presents challenges in integration, annotation, and presentation.
  • Traditional methods struggle with the complexity of data from Sanger and Next Generation Sequencing (NGS) platforms.

Purpose of the Study:

  • To develop an integrated system, STINGRAY, for streamlined analysis of genomic and expression data.
  • To provide a user-friendly platform for researchers working with diverse sequencing data.

Main Methods:

  • Implementation of a comprehensive bioinformatics workflow with over 20 integrated tools.
  • Development of a MySQL database schema for robust data integration and access control.
  • Creation of an intuitive, graphical web-based interface for ease of use.

Main Results:

  • STINGRAY offers a complete workflow from functional annotation to phylogeny.
  • The system supports data integration and user access control via its MySQL database.
  • A user-friendly web interface facilitates intuitive data analysis and annotation.

Conclusions:

  • STINGRAY is an easy-to-use and comprehensive system for analyzing sequencing data.
  • The system supports both Sanger and NGS platforms, though NGS data may impact database performance.
  • STINGRAY is accessible online with open-source code available for community use.