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Validation of parental reports of asthma trajectory, burden, and risk by using the pediatric asthma control and
Sande O Okelo1, Michelle N Eakin2, Kristin A Riekert2
1Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, Calif.
Insights
The Pediatric Asthma Control and Communication Instrument (PACCI) effectively measures parent-reported asthma morbidity, including direction, bother, and risk, demonstrating good validity for assessing pediatric asthma outcomes.
Area of Science:
- Pediatric Pulmonology
- Clinical Assessment Tools
- Patient-Reported Outcomes
Background:
- Limited pediatric asthma questionnaires address multiple morbidity dimensions as per national guidelines.
- Few tools utilize patient-reported outcomes for assessing pediatric asthma.
Purpose of the Study:
- To evaluate the Pediatric Asthma Control and Communication Instrument (PACCI) for measuring parent-reported asthma morbidity.
- Assess the PACCI's ability to capture direction, bother, and risk dimensions of pediatric asthma.
Main Methods:
- Administered the PACCI to children during routine asthma care.
- Assessed asthma control, quality of life (PACQLQ), and lung function (FEV1%).
- Evaluated the PACCI for discriminative validity.
Main Results:
- 317 children participated; mean age 8.2 years.
- Worsening PACCI Direction and increased Bother correlated with poorer asthma control and quality of life.
- PACCI Risk events were associated with poorer asthma control and quality of life.
Conclusions:
- PACCI Direction, Bother, and Risk are valid measures of parent-reported outcomes.
- The PACCI demonstrates good discriminative validity.
- PACCI is a simple tool for assessing pediatric asthma morbidity, risk, and control.
Background:
Despite a growing interest, few pediatric asthma questionnaires assess multiple dimensions of asthma morbidity, as recommended by national asthma guidelines, or use patient-reported outcomes.
Objective:
To evaluate a questionnaire that measures multiple dimensions of parent-reported asthma morbidity (Direction, Bother, and Risk).
Methods:
We administered the Pediatric Asthma Control and Communication Instrument (PACCI) and assessed asthma control (PACCI Control), quality of life, and lung function among children who presented for routine asthma care. The PACCI was evaluated for discriminative validity.
Results:
A total of 317 children participated (mean age, 8.2 years; 58% boys; 44% African American). As parent-reported PACCI Direction changed from "better" to "worse," we observed poorer asthma control (P < .001), mean Pediatric Asthma Caregiver Quality of Life Questionnaire (PACQLQ) scores (P < .001), and FEV1% (P = .025). Linear regression showed that, for each change in PACCI Direction, the mean PACQLQ score decreased by -0.6 (95% CI, -0.8 to -0.4). As parent-reported PACCI Bother changed from "not bothered" to "very bothered," we observed poorer asthma control (P < .001) and lower mean PACQLQ scores (P < .001). Linear regression showed that, for each change in PACCI Bother category, the mean PACQLQ score decreased by -1.1 (95% CI, -1.3 to -0.9). Any reported PACCI Risk event (emergency department visit, hospitalization, or use of an oral corticosteroid) was associated with poorer asthma control (P < .05) and PACQLQ scores (P < .01).
Conclusions:
PACCI Direction, Bother, and Risk are valid measures of parent-reported outcomes and show good discriminative validity. The PACCI is a simple clinical tool to assess multiple dimensions of parent-reported asthma morbidity, in addition to risk and control.
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