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Updated: May 2, 2026

Digital Microfluidics for Automated Proteomic Processing
Published on: November 6, 2009
A journey through PROTEOSONICS
J E Araújo1, E Oliveira1, P Kouvonen2
1BIOSCOPE Research group, REQUIMTE, Department of Chemistry, Faculty of Science and Technology, University NOVA of Lisbon, Portugal; PROTEOMASS Scientific Society, Madan Parque, Rua dos Inventores, 2825-182 Caparica, Portugal.
Abstract:
Ultrasonic energy is gaining momentum in Proteomics. It helps to shorten many proteomics workflows in an easy and efficient manner. Ultrasonic energy is nowadays used for protein extraction, solubilisation and cell disruption, to speed protein identification, protein quantification, peptide profiling, metal-protein complexes characterisation and imaging mass spectrometry. The present review gives a perspective of the latest achievements in ultrasonic-based sample treatment for proteomics as well as provides the basic concepts and the tools of the trade to efficiently implement this tool in proteomics labs.
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