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Application of Chronic Stimulation to Study Contractile Activity-induced Rat Skeletal Muscle Phenotypic Adaptations
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Long-term high-level exercise promotes muscle reinnervation with age

Simone Mosole1, Ugo Carraro, Helmut Kern

  • 1From the Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padua, Padua, Italy (SM, UC, AN, SZ); Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria (HK, SL, HF, SB, SZ); Department of Physical Medicine and Rehabilitation, Wilhelminenspital, Vienna, Austria (HK, MV); Center of Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria (WM, MK); Department of Physical Medicine and Rehabilitation, Medical University of Vienna, Vienna, Austria (TP-S); Faculty of Physical Education and Sport, Comenius University, Bratislava, Slovakia (DH, JC, MSedliak, VT); Science and Research Centre, Institute for Kinesilogical Research, University of Primorska, Koper, Slovenia (NS); DAHFMO-Unit of Histology and Medical Embryology, IIM, Sapienza University of Rome, Rome, Italy (AM); Venetian Institute of Molecular Medicine, Dulbecco Telethon Institute, and Department of Biomedical Science, University of Padua, Padua, Italy (MSandri); CeSI-Center for Research on Aging, and DNI-Department of Neuroscience and Imaging, University G. d'Annunzio of Chieti, Chieti, Italy (FP); and Anatomy Department, Southern Illinois University School of Medicine, Carbondale, Illinois (AP).

Journal of Neuropathology and Experimental Neurology
|March 11, 2014
PubMed
Summary

Regular exercise preserves muscle strength and fiber integrity in seniors. High-level physical activity promotes muscle reinnervation, counteracting age-related muscle loss and potentially delaying functional decline.

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