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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis III01:31

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Pulmonary Tuberculosis V01:28

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Pulmonary Tuberculosis IV01:26

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
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Orbital tuberculosis in a paediatric population.

Saurbhi Khurana1, Neelam Pushker2, Sreedhara Shankara Naik1

  • 1Senior Resident, Oculoplasty and Paediatric Ophthalmology Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Tropical Doctor
|March 11, 2014
PubMed
Summary
This summary is machine-generated.

Orbital tuberculosis (TB) in children presents with varied symptoms, including discharging sinuses and lid masses. Early diagnosis and anti-tubercular treatment are crucial for favorable outcomes, even with challenging microbiological confirmation.

Keywords:
Orbital tuberculosiscold abscess of orbitperiocular tuberculosis

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Area of Science:

  • Ophthalmology
  • Pediatrics
  • Infectious Diseases

Background:

  • Orbital tuberculosis (TB) is a rare but serious condition in children.
  • It can manifest with diverse clinical presentations, often mimicking other orbital pathologies.
  • Prompt diagnosis and management are essential to prevent long-term complications.

Purpose of the Study:

  • To describe the clinical characteristics, diagnostic approaches, and management strategies for orbital TB in pediatric patients.
  • To highlight the challenges in achieving microbiological confirmation of orbital TB.
  • To emphasize the importance of a high index of suspicion for timely diagnosis.

Main Methods:

  • Retrospective analysis of eight pediatric cases diagnosed with orbital TB.
  • Review of clinical presentations, diagnostic investigations (including Polymerase Chain Reaction and Acid Fast Bacilli staining/culture), histopathological findings, and treatment outcomes.
  • Surgical interventions included drainage, curettage, and debridement.

Main Results:

  • The study included children aged 3-16 years.
  • Common presentations were discharging sinus, cystic mass, and lid necrosis.
  • Five patients had underlying bony changes.
  • Microbiological confirmation was achieved in some cases (PCR positive in 4, AFB culture positive in 3).
  • Histopathology showed granulomatous inflammation in six cases.
  • All patients responded favorably to anti-tubercular treatment.

Conclusions:

  • Orbital TB in children requires a high index of suspicion due to varied presentations.
  • Microbiological and pathological confirmation may not always be feasible.
  • Effective management relies on prompt clinical suspicion and appropriate anti-tubercular therapy, leading to favorable outcomes.