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Published on: March 22, 2024
Severe neutropenia presenting with Candida albicans eyelid abscess in a 1-year-old child
Bryan R Costin1, Carrie E Costin, Palak B Wall
1*Cole Eye Institute, Cleveland Clinic; †Center for Human Genetics, University Hospitals Case Medical Center; and ‡Cleveland Clinic Children's Hospital, Cleveland, Ohio, U.S.A.
Abstract:
A previously healthy 1-year-old boy presented with a right lower eyelid abscess. Oral and topical antibiotics were initiated, and the lesion was drained and explored. Despite medical and surgical treatment, the abscess failed to resolve completely and formed again 1 month later. A second incision and drainage procedure was performed, and Candida albicans grew in cultures. Additional workup revealed severe neutropenia with an absolute neutrophil count of 0.18 k/μl (1.19-7.21 k/μl). The abscess resolved after 2 weeks of oral fluconazole. C. albicans eyelid abscess may be the presenting sign of systemic immunodeficiency.
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