Cardiovascular disease assessment in rheumatoid arthritis: a guide to translating knowledge of cardiovascular risk

Anne Grete Semb1, Silvia Rollefstad1, Piet van Riel2

  • 1Department of Rheumatology, Preventive Cardio-Rheuma Clinic, Diakonhjemmet Hospital, Oslo, Norway.

Insights

Physicians should assess and manage cardiovascular disease (CVD) risk in rheumatoid arthritis (RA) patients using general population guidelines. Early strategies include risk factor recording, referral, and patient education for better CVD prevention.

Area of Science:

  • Rheumatology
  • Cardiovascular Medicine
  • Preventive Cardiology

Background:

  • Limited evidence exists for cardiovascular disease (CVD) prevention and outcomes in rheumatoid arthritis (RA) patients.
  • Existing literature highlights the need for vigorous attention to CVD risk in RA.
  • There is consensus that RA patients meeting general population criteria for CVD risk reduction should receive interventions.

Purpose of the Study:

  • To advocate for the assessment and management of CVD risk in RA patients.
  • To address the evidence vacuum in CVD prevention for RA.
  • To propose initial strategies for CVD risk evaluation in RA clinical practice.

Main Methods:

  • Recommending the application of general population CVD risk calculators.
  • Suggesting referral of high-risk RA patients to primary care physicians or cardiologists.
  • Emphasizing patient education on CVD risk modification.

Main Results:

  • Advocacy for immediate CVD risk assessment and intervention in RA patients, aligning with general population recommendations.
  • Acknowledgement of ongoing uncertainties regarding CVD treatment thresholds, targets, and outcomes in RA.
  • Proposal of modest, implementable strategies for data collection in routine rheumatology consultations.

Conclusions:

  • CVD risk should be actively assessed and managed in RA patients, mirroring general population guidelines.
  • Initial implementation strategies should focus on risk factor recording, referral pathways, and patient engagement.
  • Further research, including educational programs and hard CVD endpoint studies, is needed for RA patients.

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