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Cardiovascular disease assessment in rheumatoid arthritis: a guide to translating knowledge of cardiovascular risk
Anne Grete Semb1, Silvia Rollefstad1, Piet van Riel2
1Department of Rheumatology, Preventive Cardio-Rheuma Clinic, Diakonhjemmet Hospital, Oslo, Norway.
Insights
Physicians should assess and manage cardiovascular disease (CVD) risk in rheumatoid arthritis (RA) patients using general population guidelines. Early strategies include risk factor recording, referral, and patient education for better CVD prevention.
Area of Science:
- Rheumatology
- Cardiovascular Medicine
- Preventive Cardiology
Background:
- Limited evidence exists for cardiovascular disease (CVD) prevention and outcomes in rheumatoid arthritis (RA) patients.
- Existing literature highlights the need for vigorous attention to CVD risk in RA.
- There is consensus that RA patients meeting general population criteria for CVD risk reduction should receive interventions.
Purpose of the Study:
- To advocate for the assessment and management of CVD risk in RA patients.
- To address the evidence vacuum in CVD prevention for RA.
- To propose initial strategies for CVD risk evaluation in RA clinical practice.
Main Methods:
- Recommending the application of general population CVD risk calculators.
- Suggesting referral of high-risk RA patients to primary care physicians or cardiologists.
- Emphasizing patient education on CVD risk modification.
Main Results:
- Advocacy for immediate CVD risk assessment and intervention in RA patients, aligning with general population recommendations.
- Acknowledgement of ongoing uncertainties regarding CVD treatment thresholds, targets, and outcomes in RA.
- Proposal of modest, implementable strategies for data collection in routine rheumatology consultations.
Conclusions:
- CVD risk should be actively assessed and managed in RA patients, mirroring general population guidelines.
- Initial implementation strategies should focus on risk factor recording, referral pathways, and patient engagement.
- Further research, including educational programs and hard CVD endpoint studies, is needed for RA patients.
Abstract:
As physicians we like to have evidence for making decisions about interventions to improve health. The evidence vacuum in the field of cardiovascular disease (CVD) prevention and clinical outcome in patients with rheumatoid arthritis (RA) has received vigorous attention in the recent literature. There is broad agreement that a patient with RA fulfilling the criteria established for the general population on CVD risk reduction should receive proven interventions, including smoking cessation, weight reduction, blood pressure control and lipid-lowering therapy. In accordance with these recommendations, and despite all the uncertainties about CVD treatment threshold, targets and outcome results in RA, we firmly advocate that CVD risk should be assessed and acted on in patients with RA as recommended for the general population, even while educational CVD-preventive programmes are being developed and hard CVD end point studies are undertaken in this patient population. The initial strategies for implementing CVD risk evaluation will necessarily be modest at first. There are several possible strategies for collection of data that can be incorporated into the daily routine during rheumatology consultations at outpatient clinics. We recommend starting with these simple procedures: 1. CVD risk factor recording and evaluation using risk calculators available for the general population 2. Referral of patients with high CVD risk to a primary care physician or a cardiologist skilled in this subject for follow-up 3. Providing information about excess CVD risk and how to modify it to the patients as major stakeholders.
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