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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
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Active surveillance for clinically localized prostate cancer--a systematic review
Frederik B Thomsen1, Klaus Brasso, Laurence H Klotz
1Copenhagen Prostate Cancer Center, Department of Urology, Rigshospitalet, University of Copenhagen, Denmark.
Journal of Surgical Oncology
|March 11, 2014
Summary
Active surveillance (AS) delays cancer treatment, maintaining survival rates. However, optimal patient selection and long-term safety require further research.
Area of Science:
- Oncology
- Urologic Oncology
- Cancer Surveillance
Background:
- Active surveillance (AS) is an observational strategy for managing cancer.
- It aims to delay or avoid curative treatment.
- AS seeks to preserve long-term cancer-specific survival.
Purpose of the Study:
- To review existing literature on active surveillance (AS) strategies.
- To identify areas of consensus and uncertainty in AS implementation.
- To assess the long-term safety and efficacy of AS.
Main Methods:
- A systematic review of 10 studies published between 2008 and 2013.
- Analysis of patient selection criteria and management protocols for AS.
- Evaluation of progression criteria and long-term outcomes.
Main Results:
- General agreement exists on patient selection and management within AS programs.
- Uncertainties remain regarding optimal patient selection criteria.
- Reliable progression criteria and long-term safety of AS are not fully established.
Conclusions:
- Active surveillance is a viable strategy for delaying cancer treatment.
- Further research is needed to refine patient selection and progression criteria.
- Long-term safety data for active surveillance requires additional investigation.
