Drusen and drusenoid macular lesions
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Updated: Oct 13, 2026

Enrichment of Bruch's Membrane from Human Donor Eyes
Published on: November 15, 2015
P H Morse1, E Torczynski, M Kumar
1Department of Ophthalmology, University of Chicago, Pritzker School of Medicine.
Abstract:
Yellow-colored lesions with a similar appearance at the level of the retinal pigment epithelium are frequently called drusen. Direct and indirect ophthalmoscopy, slit-lamp and contact lens examination, and fluorescein angiography allow differentiation among true drusen, retinal-pigment-epithelial detachments, and deposits secondary to retinal-pigment-epithelial degeneration. A combination of these lesions may be present in a single eye especially in patients with age-related macular degeneration. It is important to distinguish among these lesions because prognosis and treatment potential vary.
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