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A ligation DNAzyme-induced magnetic nanoparticles assembly for ultrasensitive detection of copper ions
Honghong Yin1, Hua Kuang, Liqiang Liu
1State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University , Wuxi, Jiangsu 214122, China.
ACS Applied Materials & Interfaces
|March 12, 2014
Abstract:
A novel biosensor for ultrasensitive detection of copper (Cu(2+)) was established based on the assembly of magnetic nanoparticles induced by the Cu(2+)-dependent ligation DNAzyme. With a low limit of detection of 2.8 nM and high specificity, this method has the potential to serve as a general platform for the detection of heavy metal ions.
