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Pigmented condyloma acuminatum
Akira Shimizu1, Madoka Kato, Osamu Ishikawa
1Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.
The Journal of Dermatology
|March 12, 2014
Summary
This study details a case of pigmented condyloma acuminatum, a genital lesion caused by human papillomavirus (HPV) type 6. Differentiating this condition from other skin lesions can be challenging, highlighting the importance of HPV typing for diagnosis.
Area of Science:
- Dermatology
- Virology
- Pathology
Background:
- Pigmented condyloma acuminatum is a genital lesion caused by human papillomavirus (HPV).
- Differential diagnosis can be challenging, sometimes confused with bowenoid papulosis or seborrheic keratosis.
- The mechanism of pigmentation in these lesions is not fully understood.
Observation:
- A case of pigmented condyloma acuminatum in the genital region was examined.
- Histopathology showed keratinocyte proliferation, papillomatosis, and basal pigmentation with rare cellular atypia.
- The patient also presented with ordinary skin-colored nodules.
Findings:
- Polymerase chain reaction and sequencing confirmed HPV type 6 infection.
- The histopathological findings are consistent with condyloma acuminatum with pigmentation.
- The presence of both pigmented and skin-colored lesions was noted.
Implications:
- HPV typing is a valuable diagnostic tool for pigmented condyloma acuminatum.
- Further research is needed to elucidate the mechanism of pigmentation.
- Accurate diagnosis is crucial for appropriate patient management and to exclude other conditions.
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