Related Experiment Video

Updated: May 2, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.3K

Sleep fragmentation and increased periodic limb movements are more common in children with nocturnal enuresis

K Dhondt1, E Baert, C Van Herzeele

  • 1Pediatrics, Department of Child Neurology & Metabolism. Pediatric Sleep Center, Ghent University Hospital, Ghent, Belgium.

Acta Paediatrica (Oslo, Norway : 1992)
|March 12, 2014
PubMed

Insights

Children with nocturnal enuresis (NE) experience more fragmented sleep and periodic limb movements during sleep compared to controls. These findings suggest NE

Area of Science:

  • Pediatric Sleep Medicine
  • Urology
  • Neuroscience

Background:

  • Nocturnal enuresis (NE) is common in children.
  • The relationship between NE and sleep quality is not fully understood.
  • Sleep fragmentation may play a role in NE pathophysiology.

Purpose of the Study:

  • To investigate sleep fragmentation in children with NE.
  • To compare sleep parameters between children with NE and healthy controls.
  • To explore the association between periodic limb movements and NE.

Main Methods:

  • Children with NE and age/gender-matched controls underwent overnight video-polysomnography.
  • NE parameters were assessed by pediatricians.
  • Sleep studies were analyzed for periodic limb movements, arousals, and awakenings.

Main Results:

  • Children with NE showed significantly higher periodic limb movement index, arousal index, and awakening index than controls.
  • Increased sleep fragmentation was observed in the NE group.
  • Periodic limb movements with cortical arousals were more frequent in children with NE.

Conclusions:

  • Children with NE exhibit greater sleep fragmentation and periodic limb movements.
  • These findings highlight the central nervous system's involvement in NE.
  • NE is likely a multifactorial condition with significant sleep-related components.
Abstract

Keywords:
BladderDesmopressinNocturnal enuresisPeriodic limb movements in sleepRestless legs syndrome

More Related Videos

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

10.8K
Physical Activity Measurement in Children Accepting Table Tennis Training06:51

Physical Activity Measurement in Children Accepting Table Tennis Training

Published on: July 27, 2022

2.0K

Related Concept Videos

Nightmares and Night Terrors01:18

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
1.0K
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
931
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
3.0K
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
1.8K
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
2.9K
Narcolepsy01:07

Narcolepsy

Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
891