Related Experiment Video
Updated: May 2, 2026

03:55
Author Spotlight: Enhancing Grasping Abilities for Hemiplegic Patients with Flexible Robotic Limbs
Published on: October 27, 2023
2.6K
A slowly enlarging mass on the finger
Julie Jefferson1, Curtis Thompson, Phoebe Rich
1Johns Hopkins Medicine. julieajeffersonmd@gmail.com.
Dermatology Online Journal
|March 12, 2014
Summary
A rare finger tumor, aggressive digital papillary adenocarcinoma (ADPAca), was diagnosed in a 71-year-old woman. Early surgical intervention is crucial due to its high metastatic potential.
Area of Science:
- Dermatopathology
- Surgical Oncology
Background:
- Adnexal tumors represent a diverse group of neoplasms originating from hair follicles or sebaceous glands.
- Aggressive digital papillary adenocarcinoma (ADPAca) is a rare adnexal tumor with a propensity for local recurrence and distant metastasis.
Observation:
- A 71-year-old woman presented with a slowly enlarging, asymptomatic 9-mm papule on her right 4th finger.
- Physical examination revealed a tan-pink, mobile papule with a central keratotic plug over the proximal interphalangeal joint.
Findings:
- Histopathologic examination of a punch biopsy confirmed the diagnosis of aggressive digital papillary adenocarcinoma (ADPAca).
- The tumor's rarity and nonspecific clinical presentation contribute to frequent misdiagnosis.
Implications:
- Aggressive digital papillary adenocarcinoma (ADPAca) requires prompt and radical surgical management, potentially including digital amputation.
- Sentinel lymph node biopsy may be considered in the management of ADPAca to assess for metastatic spread.
Related Concept Videos
Muscles of the Forearm that Move the Hand and Fingers
3.4K
The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi...
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi...
3.4K
Accessory Structures of the Skin: Nails
3.7K
Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
3.7K
Assessment of the Abdomen III: Palpation
5.6K
Palpation is a crucial tactile examination method for assessing abdominal organs and detecting conditions like tenderness, distention, masses, or fluid. It involves both light and deep palpation techniques, each serving specific diagnostic purposes. Light palpation helps identify tenderness and other surface-level indicators, while deep palpation locates and assess abdominal masses and organ boundaries. A skilled professional can gather valuable insights through palpation, including evaluating...
5.6K
Cardiovascular System Abnormal Findings I: Inspection and Palpation
1.3K
In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
Abnormal findings observed during an inspection
1.3K
Papillary Dermis
5.8K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
5.8K
Enlargement of the Plasma Membrane
1.8K
Cell division and enlargement are processes that require precise control. The control ensures that cell division cannot proceed unless the cell has grown to a specific size. A spherical, dividing cell requires an approximately 1.6X increase in its surface area to double its volume. The secretory pathway also has a significant role in cell membrane enlargement. Secretory vesicles that bud off from the Golgi apparatus and later fuse with the plasma membrane during exocytosis are a major source of...
1.8K