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Updated: May 2, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Atypical presentation of isolated peripheral T-cell lymphoma in the hand: case report
Theodore A Kung1, Lauren B Smith1, Kevin C Chung1
1Section of Plastic Surgery, Department of Surgery, University of Michigan Health Systems, Ann Arbor, MI; Department of Pathology, University of Michigan Health Systems, Ann Arbor, MI; Section of Plastic Surgery, University of Michigan Medical School, Ann Arbor, MI.
Abstract:
Peripheral T-cell lymphoma is a rare malignancy that characteristically demonstrates generalized lymphadenopathy and extranodal involvement. We describe an atypical case of peripheral T-cell lymphoma manifesting as isolated hand swelling without evidence of nodal disease or systemic symptoms. This report emphasizes the highly variable clinical presentation of T-cell lymphomas and the importance of expeditious incisional biopsy in the setting of an undiagnosed hand mass.

