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Hepatitis C in haemorrhagic obstetrical emergencies
Meharunnisa Khaskheli1, Shahla Baloch1, Sumiya Farooq1
1Department of Obstetrics and Gynaecology, Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad, Sindh.
Summary
Hepatitis C significantly increases the risk of obstetrical haemorrhagic emergencies, leading to higher rates of maternal and fetal complications. This highlights the critical need for screening in high-risk pregnancies.
Area of Science:
- Obstetrics and Gynecology
- Hepatology
- Maternal-Fetal Medicine
Background:
- Hepatitis C virus (HCV) infection poses significant health challenges globally.
- Pregnancy in women with HCV requires careful management due to potential complications.
- Obstetrical haemorrhagic emergencies are a leading cause of maternal morbidity and mortality.
Purpose of the Study:
- To investigate the association between Hepatitis C infection and obstetrical haemorrhagic emergencies.
- To evaluate the impact of Hepatitis C on maternal health outcomes.
- To determine the fetal outcomes in pregnancies complicated by Hepatitis C and obstetrical haemorrhage.
Main Methods:
- An observational study was conducted at Liaquat University of Medical and Health Sciences Hospital.
- Data was collected from January 2009 to December 2010, including women with obstetrical haemorrhagic emergencies.
- Hepatitis C screening was performed on all participants; non-haemorrhagic cases were excluded. Data analysis utilized SPSS version 20.
Main Results:
- Hepatitis C positive cases showed a higher frequency of obstetrical haemorrhagic emergencies (80.88% postpartum haemorrhage, 19.11% ante-partum haemorrhage).
- Associated morbidities in Hepatitis C positive women included disseminated intravascular coagulation (11.91%) and shock (8.03%).
- The fetal stillbirth rate was notably higher in Hepatitis C positive cases (10.24%).
Conclusions:
- Hepatitis C infection is associated with an increased frequency of maternal morbidity and mortality in obstetrical haemorrhagic emergencies.
- Perinatal mortality rates are significantly elevated in pregnant women with Hepatitis C experiencing haemorrhagic complications.
- These findings underscore the importance of considering Hepatitis C status in managing obstetrical emergencies.
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