Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functions of Life01:23

Functions of Life

17.0K
Human life is characterized by a variety of functions that are essential for survival and well-being. These functions include metabolism, movement, development, growth and reproduction.
Metabolism
The basic function of an organism is to consume energy and molecules in foods, convert some of it into fuel for movement, sustain body functions, and build and maintain body structures. There are two types of reactions that accomplish this: anabolism and catabolism.
Anabolism is the process whereby...
17.0K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

14.8K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
14.8K
Hedgehog Signaling Pathway02:33

Hedgehog Signaling Pathway

7.1K
The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like hedgehog spines. Hh plays a crucial role in the development of organs and the maintenance of homeostasis in both invertebrates and vertebrates. However, while Drosophila has only one Hh protein, mammals have multiple functional Hedgehog proteins - Sonic (Shh), Desert (Dhh), and Indian Hedgehog (Ihh). All of these homologous proteins have adapted to...
7.1K
Hedgehog Signaling Pathway02:33

Hedgehog Signaling Pathway

1.5K
1.5K
From DNA to Protein03:06

From DNA to Protein

20.7K
The flow of genetic information in cells from DNA to mRNA to protein is described by the central dogma, which states that genes specify the sequence of mRNAs, which in turn specify the sequence of amino acids making up all proteins. The decoding of one molecule to another is performed by specific proteins and RNAs. Because the information stored in DNA is so central to cellular function, it makes intuitive sense that the cell would make mRNA copies of this information for protein synthesis...
20.7K
The Central Dogma01:20

The Central Dogma

21.2K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
21.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Innovations in applications of mass spectrometry impact many fields of science.

Mass spectrometry reviews·2023
Same author

MALDI-TOF Mass Spectrometric Detection of SARS-CoV-2 Using Cellulose Sulfate Ester Enrichment and Hot Acid Treatment.

Journal of proteome research·2022
Same author

Molecular cargo in myeloid-derived suppressor cells and their exosomes.

Cellular immunology·2020
Same author

Extraction of Membrane Components from <i>Neisseria gonorrhoeae</i> Using Catanionic Surfactant Vesicles: A New Approach for the Study of Bacterial Surface Molecules.

Pharmaceutics·2020
Same author

Microwave supported hydrolysis prepares <i>Bacillus</i> spores for proteomic analysis.

International journal of mass spectrometry·2020
Same author

Analysis of the topology of ubiquitin chains.

Methods in enzymology·2019

Related Experiment Video

Updated: May 2, 2026

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

8.3K

From genes to function: kick-starting US HUPO.

Catherine Fenselau1

  • 1Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, United States.

Journal of Proteomics
|March 12, 2014
PubMed
Summary

The U.S. Human Proteome Organization (HUPO) advances proteomics research and education. This special issue commemorates 20 years of proteomics advancements.

Area of Science:

  • Proteomics
  • Human Proteome Research
  • Model Organism Proteomics

Background:

  • The U.S. Human Proteome Organization (HUPO) is dedicated to advancing scientific and educational initiatives.
  • Proteomics plays a crucial role in understanding biological systems.

Purpose of the Study:

  • To encourage the dissemination of proteomics technologies.
  • To share knowledge regarding the human proteome and model organisms.

Main Methods:

  • This article is part of a special commemorative issue.
  • Content focuses on advancements in proteomics over two decades.

Main Results:

  • The issue highlights the progress and impact of proteomics.
  • Showcases the breadth of knowledge in human and model organism proteomics.
Keywords:
HistoryProteomicsUS HUPO

More Related Videos

Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening
05:06

Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening

Published on: May 24, 2024

1.4K
Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
08:09

Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics

Published on: June 17, 2012

23.1K

Related Experiment Videos

Last Updated: May 2, 2026

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

Published on: May 28, 2021

8.3K
Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening
05:06

Author Spotlight: Cardiac Cell Transgenesis for Rapid Gene Screening

Published on: May 24, 2024

1.4K
Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
08:09

Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics

Published on: June 17, 2012

23.1K

Conclusions:

  • The U.S. HUPO actively promotes the growth and understanding of proteomics.
  • This special issue serves as a testament to the field's evolution over 20 years.