Impact of risk scoring on decision-making in symptomatic moderate carotid atherosclerosis
B Dharmarajah1, A Thapar, J Salem
1Academic Section of Vascular Surgery, Whittington Health NHS Trust, London, UK; Division of Experimental Medicine, Imperial College London, Whittington Health NHS Trust, London, UK.
Insights
The European Carotid Surgery Trial (ECST) risk score influences clinical decisions for carotid endarterectomy (CEA). Clinicians opted for CEA in high-risk cases and best medical therapy in low-risk cases when presented with the ECST score.
Area of Science:
- Vascular Surgery
- Neurology
- Clinical Decision-Making
Background:
- Carotid endarterectomy (CEA) benefits for moderate symptomatic carotid stenosis are marginal.
- National guidelines recommend the European Carotid Surgery Trial (ECST) risk score for symptomatic carotid disease.
- The impact of the ECST risk score on clinician decision-making is unknown.
Purpose of the Study:
- To evaluate whether the ECST risk score influences clinical decisions regarding CEA.
- To assess how clinicians' treatment preferences change with the introduction of the ECST risk score.
Main Methods:
- Three patient scenarios with varying 5-year stroke risks (low, moderate, high) were created using the ECST risk model.
- An online survey was distributed to vascular surgeons and stroke physicians, collecting initial responses.
- The survey was repeated with the ECST risk score included to gauge its influence on decisions.
Main Results:
- The ECST risk score increased CEA use in high-risk scenarios (66.7% vs. 80.1%; P=0.009).
- Low-risk scenarios showed a significant shift towards best medical therapy after risk score introduction (23.4% vs. 57.2%; P<0.001).
- Vascular surgeons showed a greater preference for CEA than stroke physicians in low- and moderate-risk scenarios.
Conclusions:
- The ECST risk score appears to guide clinicians toward CEA for high-risk patients.
- The risk score promotes the use of best medical therapy for low-risk patients.
- Clinician specialty influences treatment preference, with surgeons favoring CEA more often.
Background:
Benefit from carotid endarterectomy (CEA) in symptomatic moderate (50-69 per cent) carotid stenosis remains marginal. The Fourth National Clinical Guideline for Stroke recommends use of the risk score from the European Carotid Surgery Trial (ECST) to aid decision-making in symptomatic carotid disease. It is not known whether clinicians are, in fact, influenced by it.
Methods:
Using the ECST risk prediction model, three scenarios of patients with a low (less than 10 per cent), moderate (20-25 per cent) and high (40-45 per cent) 5-year risk of stroke were devised and validated. Invitations to complete an online survey were sent by e-mail to vascular surgeons and stroke physicians, with responses gathered. The questionnaire was then repeated with the addition of the ECST risk score.
Results:
Two hundred and one completed surveys were analysed (21·5 per cent response rate): 107 by stroke physicians and 94 by vascular surgeons. The high-risk scenario after the introduction of the ECST risk score showed an increased use of CEA (66·7 versus 80·1 per cent; P = 0·009). The low-risk scenario after risk score analysis demonstrated a swing towards best medical therapy (23·4 versus 57·2 per cent; P < 0·001). CEA was preferred in the moderate-risk scenario and this was not altered significantly by introduction of the risk score (71·6 versus 75·6 per cent; P = 0·609). Vascular surgeons exhibited a preference towards CEA compared with stroke physicians in both low- and moderate-risk scenarios (P < 0·001 and P = 0·003 respectively).
Conclusion:
The addition of a risk score appeared to influence clinicians in their decision-making towards CEA in high-risk patients and towards best medical therapy in low-risk patients.
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