Metabolic inactivation of bleomycin analogs by bleomycin hydrolase

Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours.

British journal of cancer·2014

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities.

Oncogene·2013

Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion.

Oncogene·2011

The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane.

Cell death and differentiation·2010

Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase.

Neuroscience·2007

A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway.

Oncogene·2007

Antimicrobial photodynamic therapy across ESKAPE pathogens: Efficacy, limitations, and a pathogen-adapted framework toward clinical translation.

Pharmacology & therapeutics·2026

Prospects for treatment of cerebral ischemic stroke with Hydroxysafflower Yellow A.

Pharmacology & therapeutics·2026

Targeting metabolic reprogramming in cancer: Past, present, and future.

Pharmacology & therapeutics·2026

Targeting glycine transporter type 1 (GlyT1) in epilepsy: Pathophysiological rationale and therapeutic perspectives.

Pharmacology & therapeutics·2026

The brain angiotensin converting enzyme 2 and angiotensin-(1-7) as potential therapeutic targets for the central nervous system diseases.

Pharmacology & therapeutics·2026

Mechanisms of 'metabolizeaccretion' and therapeutic targets in influenza infection.

Pharmacology & therapeutics·2026

Mitochondria in health and disease: cellular powerhouses, signaling centers, and drivers of dysfunction.

Frontiers in cell and developmental biology·2026

Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes.

Frontiers in network physiology·2026

Rotenone-induced oxidative stress triggers peroxisomal alterations in BV-2 microglial cells.

Frontiers in cellular neuroscience·2026

A primary hepatopancreatic cell platform enables cellular dissection of glucose metabolism and endocrine-metabolic regulation in Litopenaeus vannamei.

Frontiers in endocrinology·2026

Why is the chloroplast redox regulatory machinery so complex?

Molecular plant·2026

Parallel intracellular redox and extracellular respiration sensing for quantitative oxidative stress profiling.

Biosensors & bioelectronics·2026

Related Experiment Videos

Metabolic inactivation of bleomycin analogs by bleomycin hydrolase

Related Concept Videos

Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours.

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities.

Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion.

The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane.

Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase.

A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway.

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Prospects for treatment of cerebral ischemic stroke with Hydroxysafflower Yellow A.

Targeting metabolic reprogramming in cancer: Past, present, and future.

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Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes.

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