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Updated: Oct 1, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
08:27

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat

Published on: October 29, 2014

[Neonatal meningitis. Study of 26 cases and a review of its sequelae after 5 years]

A Cervantes Pardo1, M C Tauler Girona, C López Soler

  • 1Secciones de Neuropediatría y Psicología, Hospital Infantil Virgen de la Arrixaca, Murcia.

Anales Espanoles De Pediatria
|June 1, 1988
PubMed

Insights

Neonatal bacterial meningitis is linked to long-term neuropsychological deficits in children, including issues with attention and learning. Lymphocytic meningitis, however, shows better developmental outcomes.

Area of Science:

  • Neonatal care
  • Pediatric neurology
  • Infectious diseases

Context:

  • Study of 26 term newborns with neonatal meningitis.
  • Analysis of incidence, etiology, treatment, clinical course, and mortality.
  • Focus on long-term neurodevelopmental outcomes.

Purpose:

  • To investigate the relationship between neonatal meningitis and psychomotor growth deficits at 4 and 6 years of age.
  • To compare outcomes between bacterial and lymphocytic meningitis.
  • To identify specific neuropsychological deficits associated with neonatal meningitis.

Summary:

  • Bacterial neonatal meningitis is associated with significant neuropsychological deficits, including hyperkinesia and reading-writing disorders.
  • Children with bacterial meningitis showed impaired psychomotor development compared to those with lymphocytic meningitis.
  • Lymphocytic meningitis cases demonstrated a generally good neurodevelopmental evolution.

Impact:

  • Highlights the critical need for early diagnosis and intervention in neonatal meningitis.
  • Emphasizes the long-term consequences of bacterial meningitis on child development.
  • Informs clinical practice regarding prognosis and follow-up for affected newborns.

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