Related Experiment Video

Updated: May 2, 2026

High-throughput Assay to Phenotype Salmonella enterica Typhimurium Association, Invasion, and Replication in Macrophages
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Published on: August 11, 2014

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Autophagy facilitates Salmonella replication in HeLa cells

Hong B Yu, Matthew A Croxen, Amanda M Marchiando

    Mbio
    |March 13, 2014
    PubMed
    Summary

    Autophagy, a cellular process, unexpectedly aids Salmonella replication in the cytosol of HeLa cells. Depleting autophagy components significantly reduces bacterial growth, suggesting a novel role for autophagy in supporting pathogen survival.

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