Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....

Serum Studies: Renal Function Tests

Serum Studies: Renal Function Tests

Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.

Nursing Assessment of the Genitourinary System I: Health History

Nursing Assessment of the Genitourinary System I: Health History

The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...

Factors Affecting Renal Clearance: Renal Impairment

Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Gut microbiota alterations in renal transplant recipients and the risk of urinary tract infection and delayed graft function: A preliminary prospective study.

Urologia·2024

Same author

Phoenix dactylifera L. pollen versus pentoxifylline on improvement of sperm parameters in idiopathic male infertility: A randomized clinical trial.

Journal of ethnopharmacology·2024

Same author

The biofilm formation and antibiotic resistance of bacterial profile from endotracheal tube of patients admitted to intensive care unit in southwest of Iran.

PloS one·2022

Same author

The influence of socioeconomic factors on deceased organ donation in Iran.

Korean journal of transplantation·2022

Same author

Predicting the survival of kidney transplantation: design and evaluation of a smartphone-based application.

BMC nephrology·2022

Same author

Overexpression of long intergenic noncoding RNAs in bladder cancer: A new insight to cancer diagnosis.

Pathology, research and practice·2022

Search research articles

Related Experiment Video

Updated: May 2, 2026

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

Serum uric acid as a risk predictor for erectile dysfunction.

Sepehr Salem¹, Abdolrasoul Mehrsai, Reza Heydari

¹Urology Research Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran; Urology Institute, University Hospitals Case Medical Center, Department of Urology, Case Western Reserve University, Cleveland, OH, USA.

The Journal of Sexual Medicine

|March 14, 2014

Summary

High serum uric acid (UA) levels are a significant predictor of erectile dysfunction (ED). Hyperuricemia is an independent risk factor for ED, alongside other established conditions.

Keywords:

Cardiovascular Disease Erectile Dysfunction Metabolic Syndrome Predicting Marker Risk Factors Serum Uric Acid

More Related Videos

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

Related Experiment Videos

Last Updated: May 2, 2026

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril

Published on: October 3, 2020

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

Published on: August 14, 2019

Area of Science:

Urology
Cardiovascular Medicine
Metabolic Disorders

Background:

Serum uric acid (UA) is recognized as a cardiovascular disease risk predictor.
The association between hyperuricemia and systemic vascular disorders, particularly erectile dysfunction (ED), remains under-explored.

Purpose of the Study:

To investigate serum UA as a potential predictive factor for ED.
To assess the relationship between serum UA levels and ED risk, adjusting for common risk factors.

Main Methods:

A case-control study involving 251 patients with newly diagnosed ED and 252 age-matched controls without ED.
Logistic regression analysis was used to determine the odds ratio (OR) and 95% confidence interval (CI) for ED associated with serum UA.
Adjustments were made for confounding factors such as obesity, hypertension, diabetes, dyslipidemia, triglycerides, and smoking.

Main Results:

Mean serum UA levels were significantly higher in the ED group (6.12 ± 1.55 mg/dL) compared to the control group (4.97 ± 1.09 mg/dL).
After adjusting for risk factors, higher serum UA concentration showed a significant trend of increasing ED risk (OR 5.95).
Each 1 mg/dL increase in serum UA was associated with a twofold increase in ED risk (OR 2.07).

Conclusions:

Serum uric acid is a significant risk predictor for erectile dysfunction.
Hyperuricemia is identified as an independent risk factor for ED, in addition to established risk factors.