Densified electrochemical sensors based on local redox cycling between vertically separated electrodes in substrate
Kosuke Ino1, Yusuke Kanno, Taku Nishijo
1Graduate School of Environmental Studies and §WPI Advanced Institute for Materials Research, Tohoku University , Sendai, Japan 980-8579.
Abstract:
A new local redox cycling-based electrochemical (LRC-EC) device integrated with many electrochemical sensors has been developed into a small chip device. The LRC-EC chip device was successfully applied for detection of alkaline phosphatase and horseradish peroxidase activity in substrate generation/chip collection (SG/CC) and extended feedback modes, respectively. The new imaging approach with extended feedback mode was particularly effective for sharpening of the image, because this mode uses feedback signals and minimizes the undesired influence of diffusion. The LRC-EC chip device is considered to be a useful tool for bioanalysis.
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