Related Experiment Video
Updated: May 2, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move
E Valiente1, M D Cairns, B W Wren
1Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, UK.
None:
Clostridium difficile is a Gram-positive, spore-forming, human and animal pathogen that is the major cause of antibiotic-associated diarrhoea worldwide. The past decade has seen the rapid emergence of the hypervirulent PCR ribotype (RT) 027 complex, which has been associated with increases in the incidence and severity of disease and mortality. In this review, we describe the potential virulence factors that have been reported in strains from the RT 027 complex. We review the emergence, population structure, dissemination and evolution of this lineage.
More Related Videos
Related Concept Videos
Bacterial Gastroenteritis
Colonisation of Pathogens
Modern Molecular Taxonomy
Clinical Significance of Antibiotic Resistance
Regulation of Bacterial Virulence
Bacterial Phylum Tenericutes

