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STIM1 and SLC24A4 Are Critical for Enamel Maturation

S Wang1, M Choi2, A S Richardson3

  • 1Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, 1210 Eisenhower Place, Ann Arbor, MI, USA Oral Health Sciences Program, University of Michigan School of Dentistry, 1011 North University, Ann Arbor, MI, USA.

Journal of Dental Research
|March 14, 2014
PubMed
Summary

Genetic defects in STIM1 and SLC24A4 cause enamel hypomaturation. These genes are crucial for calcium transport in ameloblasts during enamel maturation, highlighting distinct mechanisms from earlier secretory stages.

Keywords:
amelogenesis imperfectacalciuminherited diseasesmutationstooth

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