Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Capillary Electrophoresis: Applications

Capillary Electrophoresis: Applications

Capillary electrophoretic separations offer various modes, each with unique applications. These modes include capillary zone electrophoresis, capillary gel electrophoresis, capillary array electrophoresis, capillary isoelectric focusing, capillary isotachophoresis, micellar electrokinetic chromatography, and capillary electrochromatography.
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ionic current blockade in a nanopore due to an ellipsoidal particle.

Physical review. E·2024

Same author

Neural Basis of Number Sense in Larval Zebrafish.

bioRxiv : the preprint server for biology·2024

Same author

Microscopy and modelling investigations on the morphology of the biofilm exopolysaccharide produced by Burkholderia multivorans strain C1576.

International journal of biological macromolecules·2023

Same author

VoDEx: a Python library for time annotation and management of volumetric functional imaging data.

Bioinformatics (Oxford, England)·2023

Same author

VoDEx: a Python library for time annotation and management of volumetric functional imaging data.

ArXiv·2023

Same author

Potential of mean force conformational energy maps for disaccharide linkages of the Burkholderia multivorans exopolysaccharide C1576 in aqueous solution.

Carbohydrate research·2023

Search research articles

Related Experiment Video

Updated: May 2, 2026

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Published on: October 26, 2016

Charged particle separation by an electrically tunable nanoporous membrane.

Ining A Jou¹, Dmitriy V Melnikov, Anna Nadtochiy

¹Department of Physics, Clarkson University, Potsdam, NY 13699, USA.

|March 14, 2014

Summary

This study demonstrates an electrically tunable nanoporous semiconductor membrane for nanoparticle separation by charge. Optimized electric fields allow the same membrane to separate charged particles of the same size with up to three times greater permeability.

More Related Videos

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

Utilization of Plasmonic and Photonic Crystal Nanostructures for Enhanced Micro- and Nanoparticle Manipulation

Utilization of Plasmonic and Photonic Crystal Nanostructures for Enhanced Micro- and Nanoparticle Manipulation

Published on: September 27, 2011

Related Experiment Videos

Last Updated: May 2, 2026

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Determination of Zeta Potential via Nanoparticle Translocation Velocities through a Tunable Nanopore: Using DNA-modified Particles as an Example

Published on: October 26, 2016

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

Utilization of Plasmonic and Photonic Crystal Nanostructures for Enhanced Micro- and Nanoparticle Manipulation

Utilization of Plasmonic and Photonic Crystal Nanostructures for Enhanced Micro- and Nanoparticle Manipulation

Published on: September 27, 2011

Area of Science:

Materials Science
Nanotechnology
Physical Chemistry

Background:

Nanoporous membranes are crucial for particle separation.
Current limitations include a trade-off between selectivity and permeability.
Charge-based separation of nanoparticles remains a challenge.

Purpose of the Study:

To investigate the use of an electrically tunable nanoporous semiconductor membrane for charge-based nanoparticle separation.
To overcome the selectivity-permeability compromise in nanoporous membranes.
To develop a computational model for predicting particle behavior in such systems.

Main Methods:

Development of a computational model incorporating electrostatic potential, Brownian dynamics, dielectrophoresis, fluid flow, and electric potentials.
Simulation of charged and uncharged particle movement through a specific nanoporous semiconductor membrane geometry.
Analysis of membrane permeability under varying electrolyte and membrane biases.

Main Results:

Dielectrophoresis was found to have a negligible effect on particle dynamics for the studied pore geometry.
The tunable membrane demonstrated the ability to separate same-sized particles based on charge.
Optimal electrical biases achieved up to a three-fold difference in membrane permeability for charged versus uncharged particles.

Conclusions:

Electrically tunable nanoporous semiconductor membranes offer a promising solution for selective nanoparticle separation.
This technology can decouple membrane selectivity from permeability, addressing a key limitation in particle filtration.
The developed computational model accurately predicts particle behavior and aids in optimizing membrane performance for charge-based separations.