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Published on: April 28, 2026
Gastrointestinal tract perforation: evaluation of MDCT according to perforation site and elapsed time
Hyun Cheol Kim1, Dal Mo Yang, Sang Won Kim
1Department of Radiology, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, 149 Sangil-dong, Gangdong-gu, Seoul, 134-727, Republic of Korea, khcppp@khu.ac.kr.
Objectives:
To evaluate multidetector computed tomography (MDCT) for the prediction of perforation site according to each gastrointestinal (GI) tract site and elapsed time.
Methods:
One hundred and sixty-eight patients who underwent MDCT before laparotomy for GI tract perforation were enrolled and allocated to an early or late lapse group based on an elapsed time of 7 h. Two reviewers independently evaluated the perforation site and assessed the following CT findings: free air location, mottled extraluminal air bubbles, focal bowel wall discontinuity, segmental bowel wall thickening, perivisceral fat stranding and localised fluid collection.
Results:
The overall diagnostic accuracy was 91.07 % and 91.67 % for reviewers 1 and 2, respectively, with excellent agreement (kappa 0.86). Accuracies (98.97 % and 97.94 %) and agreements (kappa 0.894) for stomach and duodenum perforation were higher than for other perforation sites. Strong predictors of perforation at each site were: focal bowel wall discontinuity for stomach, duodenal bulb and left colon, mottled extraluminal air bubbles for retroperitoneal duodenum and right colon, and segmental bowel wall thickening for small bowel. The diagnostic accuracy was not different between the early- and late-lapse groups.
Conclusions:
MDCT can accurately predict upper GI tract perforation with high reliability. Elapsed time did not affect the accuracy of perforation site prediction.
Key Points:
Perforation of the stomach and duodenum can be accurately predicted with MDCT. Knowledge of CT findings predicting perforation site can improve diagnostic accuracy. Elapsed time does not significantly affect accuracy in predicting perforation sites.
Insights
Multidetector computed tomography (MDCT) accurately predicts gastrointestinal (GI) perforation sites, especially in the stomach and duodenum. Diagnostic accuracy was high regardless of the time elapsed since perforation.
Area of Science:
- Radiology
- Gastroenterology
- Surgical Imaging
Background:
- Gastrointestinal (GI) tract perforation is a critical condition requiring prompt diagnosis.
- Accurate localization of the perforation site is crucial for effective surgical management.
- Multidetector computed tomography (MDCT) is a key imaging modality in evaluating acute abdominal conditions.
Purpose of the Study:
- To assess the efficacy of MDCT in predicting the specific site of GI tract perforation.
- To evaluate the influence of elapsed time on MDCT's perforation site prediction accuracy.
- To identify specific CT findings indicative of perforation at different GI tract locations.
Main Methods:
- A study involving 168 patients who underwent MDCT prior to laparotomy for GI perforation.
- Patients were categorized into early (<7 hours) or late (≥7 hours) groups based on time elapsed.
- Two independent reviewers analyzed MDCT scans for specific findings like extraluminal air, bowel wall changes, and fat stranding.
Main Results:
- Overall diagnostic accuracy for perforation site prediction was high (over 91%) with excellent inter-reviewer agreement (kappa 0.86).
- MDCT demonstrated superior accuracy (over 97%) for stomach and duodenum perforations.
- Specific CT findings like focal bowel wall discontinuity and mottled extraluminal air bubbles were strong predictors for different perforation sites.
Conclusions:
- MDCT is a reliable tool for accurately predicting upper GI tract perforation sites.
- The accuracy of MDCT in predicting perforation sites is not significantly affected by the elapsed time.
- Utilizing knowledge of specific CT findings enhances diagnostic accuracy for GI perforation.
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