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A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Muddy clinical waters: a missed pulmonary embolus
Nathaniel Lee1, Simon Rupert Bax
1Worthing Hospital, Worthing, UK.
Abstract:
The diagnosis of pulmonary embolism (PE) can be difficult to make. The consequences of missing a PE can be fatal and clinicians should always be vigilant. This case presents a patient admitted with fluctuations in consciousness and in a septic state. A preliminary diagnosis of aspiration pneumonia was made, and the patient went on to have an exploratory surgical procedure with no remarkable findings. Only after further investigation of the patient's fluctuations in consciousness was a retrospective diagnosis of a large PE made. The patient was anticoagulated and made a full recovery, with no outstanding pulmonary issues at follow-up 6 weeks after discharge. A prolonged immobile state, likely in part due to the patient's septic state and psychiatric history, along with recent surgery and hospitalisation were the most obvious risk factors.
Insights
Diagnosing pulmonary embolism (PE) is challenging. This case highlights a patient initially misdiagnosed, emphasizing vigilance for PE in septic patients with altered consciousness.
Area of Science:
- Medical Case Study
- Pulmonary Medicine
- Critical Care
Background:
- Pulmonary embolism (PE) diagnosis can be challenging, with potentially fatal consequences.
- Clinicians must maintain vigilance for PE, especially in complex patient presentations.
Observation:
- A patient presented with fluctuating consciousness and sepsis, initially diagnosed with aspiration pneumonia.
- An exploratory surgery revealed no significant findings, prompting further investigation into the altered consciousness.
Findings:
- A large pulmonary embolism (PE) was retrospectively diagnosed as the cause of the patient's symptoms.
- The patient received anticoagulation therapy and experienced a full recovery without pulmonary sequelae.
Implications:
- Prolonged immobility, sepsis, psychiatric history, recent surgery, and hospitalization are significant risk factors for PE.
- This case underscores the importance of considering PE in patients with unexplained altered mental status and sepsis.
- Timely diagnosis and anticoagulation are crucial for favorable outcomes in PE patients.
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