Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ovaries

Ovaries

The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Artificial Intelligence Helps Pathologists Increase Diagnostic Accuracy and Efficiency in the Detection of Breast Cancer Lymph Node Metastases.

The American journal of surgical pathology·2024

Same author

Epigenetic Regulation of Driver Genes in Testicular Tumorigenesis.

International journal of molecular sciences·2023

Same author

Artificial Intelligence-assisted Prostate Cancer Diagnosis: Radiologic-Pathologic Correlation.

Radiographics : a review publication of the Radiological Society of North America, Inc·2021

Same author

Dissecting the Business Case for Adoption and Implementation of Digital Pathology: A White Paper from the Digital Pathology Association.

Journal of pathology informatics·2021

Same author

Microscope? No, Thanks: User Experience With Complete Digital Pathology for Routine Diagnosis.

Archives of pathology & laboratory medicine·2020

Same author

Complete Digital Pathology for Routine Histopathology Diagnosis in a Multicenter Hospital Network.

Archives of pathology & laboratory medicine·2019

Search research articles

Related Experiment Video

Updated: May 2, 2026

Author Spotlight: Advanced Ex Vivo Model for Investigating Cancer-Adipose Microenvironment Interaction

Author Spotlight: Advanced Ex Vivo Model for Investigating Cancer-Adipose Microenvironment Interaction

Published on: January 26, 2024

Ovarian paraganglioma.

Maolly Schuldt¹, Juan Antonio Retamero¹, Malvina Tourné²

¹University of Granada, Granada, Spain.

International Journal of Surgical Pathology

|March 15, 2014

Summary

This summary is machine-generated.

This study reports a rare ovarian paraganglioma, an unusual tumor found incidentally in a patient undergoing surgery for endometrial cancer. Accurate diagnosis requires awareness of its distinct histological and immunohistochemical features.

Keywords:

Sertoli cell tumor immunohistochemistry neural markers ovary paraganglioma

More Related Videos

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

Published on: May 20, 2014

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Published on: July 18, 2016

Related Experiment Videos

Last Updated: May 2, 2026

Author Spotlight: Advanced Ex Vivo Model for Investigating Cancer-Adipose Microenvironment Interaction

Author Spotlight: Advanced Ex Vivo Model for Investigating Cancer-Adipose Microenvironment Interaction

Published on: January 26, 2024

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

Published on: May 20, 2014

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

Published on: July 18, 2016

Area of Science:

Gynecologic Pathology
Endocrine Pathology
Oncology

Background:

Paragangliomas are rare neuroendocrine tumors typically arising in the adrenal medulla or sympathetic ganglia.
Ovarian paragangliomas are exceptionally rare, posing diagnostic challenges due to their unusual location.

Observation:

A 1.2-cm intraovarian mass was incidentally discovered in a 68-year-old female patient with endometrial carcinoma.
Histological examination revealed characteristic Zellballen architecture with polygonal clear cells exhibiting granular cytoplasm.

Findings:

Immunohistochemistry demonstrated diffuse expression of cytokeratin (CAM5.2), chromogranin, neuron-specific enolase, synaptophysin, and CD56.
S-100 protein was confined to sustentacular cells, aiding in differential diagnosis.
Distinguishing features from Sertoli cell tumors and ependymomas were highlighted, emphasizing the importance of Zellballen morphology and specific immunophenotypes.

Implications:

This case underscores the importance of considering paraganglioma in the differential diagnosis of rare ovarian neoplasms.
Pathologists must be aware of the potential for paraganglioma in unusual locations.
Accurate identification is crucial for appropriate patient management and prognosis.