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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Case for diagnosis. Cutaneous involvement associated to multiple myeloma
Guida Santos1, Lourdes Sousa2, Teresa Fernandes3
1Centro Hospital de Lisboa Central, Santo António dos Capuchos Hospital, Lisbon, Portugal, Dermatology and Venereology Resident at the Santo António dos Capuchos Hospital - Centro Hospital de Lisboa Central (CHLC) - Lisbon, Portugal.
Abstract:
Cutaneous involvement associated to multiple myeloma varies from 5 to 10% of cases and is infrequently recognized. Cutaneous metastatic plasmacitomas are rare. We present the case of a 72-year-old man with multiple myeloma in complete remission since 2 years ago with cutaneous tumors on the trunk and face. A cutaneous biopsy was consistent with plasmacytoma. The patient was treated with melphalan, prednisolone and radiotherapy. Despite optimal therapeutic response of the lesions, the disease progressed, with the appearance of new extra-cutaneous plasmocytomas. The cutaneous metastatic plasmocytomas were the first sign of progression of the disease.
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