[Relation between blood hydrolases and small-intestinal contents]

Absorption of enzymes in the small intestine and some mechanisms providing the enzymatic homeostasis in the body were studied in isolated portions of the small intestine of rats in chronic experiments on rats and dogs, and in clinically observed subjects. A conclusion has been made that under normal conditions the level of enzyme resorption is low, and it is localized in the distal portions of the small intestine. Changes in the hydrolytic activity of blood and urine are the result of not only the resorption of pancreatic enzymes from the small intestine, but also of the shifts in their incretion by the pancreas when enzymes are introduced into the duodenum, and the secretion of enzymes in the pancreatic juice is lowered, while their incretion by the pancreas into the blood flow is increased.