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Published on: March 5, 2022
Plasma apelin levels in patients with polycystic ovary syndrome
Kıvılcım Gören1, Nevin Sağsöz2, Volkan Noyan2
1Department of Gynecology and Obstetrics, Haci Hidayet Dogruer State Hospital, Specialist of Obstetric and Gynecology, Kırıkkale, Turkey.
Objective:
The aim of the study was to evaluate plasma apelin levels in patients with polycystic ovary syndrome (PCOS) and healthy controls.
Material And Methods:
Plasma apelin levels, serum lipid levels, serum hormone levels, and homeostasis model assessment-insulin resistance (HOMA-IR) values of 32 patients with PCOS and 31 healthy women forming the control group were checked.
Results:
Plasma apelin levels of the PCOS group (0.350±0.083 ng/ml) were significantly higher than those of the control group (0.246±0.045 ng/ml) (p<0.001). No significant correlation was detected between apelin levels and biochemical or clinical data in PCOS group.
Conclusion:
Plasma apelin levels were significantly higher in PCOS patients.
