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Updated: May 2, 2026

Preparation of Homogeneous MALDI Samples for Quantitative Applications
Published on: October 28, 2016
Temperature-dependent deliquescence relative humidities and water activities using humidity controlled
Keith D Beyer1, Jason R Schroeder, Jared A Kissinger
1Department of Chemistry, University of Wisconsin-La Crosse , La Crosse, Wisconsin 54601, United States.
Abstract:
We utilize a new experimental technique, humidity-controlled thermogravimetric analysis (HTGA), to determine temperature-dependent deliquescence relative humidities (DRH) and to determine the equilibrium concentration of a solution at a given temperature and relative humidity. To that end, we have investigated the malonic acid/water system determining the DRH and concentration/RH relationship in the temperature range 303-278 K. Excellent agreement is found with literature values for the DRH of malonic acid as a function of temperature and for the concentration/RH relationship at several temperatures. Thus, we extend the DRH and concentration/RH relationship to a broader temperature range and are using the HTGA experiments to investigate other organic acids.
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