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Updated: May 2, 2026

In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells
Published on: September 28, 2017
[Shift work and risk of cancer and coronary heart diseases]
Johnni Hansen1, Christina Funch Lassen
1Center for Kræftforskning, Kræftens Bekæmpelse, Strandboulevarden 49, 2100 København Ø. johnni@cancer.dk.
Abstract:
Shift and night work are among the most frequent occupational exposures. Such work schedules involve exposure to light-at-night, which may reduce normal nocturnal melatonin production, create circadian rhythm disruption, sleep deprivation and unhealthy lifestyle. There is strong experimental evidence that light-at-night and circadian disruption may increase the risk of cancer and coronary heart diseases. There is emerging, but limited epidemiologic evidence that night shift work may increase breast cancer and certain cardiovascular diseases.
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