Henoch-Schönlein purpura: hitting the 'target' on CT
Varun Dhir1, Benzeeta Pinto1, Hari Prasad Anakutti1
1Department of Internal Medicine (Rheumatology Unit), Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Summary
This study shows common CT scan findings in Henoch-Schonlein Purpura (HSP), focusing on the characteristic "target sign" and "comb sign" to aid diagnosis.
Area of Science:
- Radiology
- Pediatric Imaging
- Gastrointestinal Imaging
Background:
- Henoch-Schonlein Purpura (HSP) is a common vasculitis affecting small blood vessels.
- Diagnosis often relies on clinical presentation and biopsy, but imaging plays a supportive role.
Observation:
- Computed Tomography (CT) provides valuable insights into the gastrointestinal manifestations of HSP.
- Characteristic imaging patterns, including the "target sign" and "comb sign," are frequently observed.
Findings:
- The "target sign" on CT indicates concentric layers of bowel wall edema and hemorrhage.
- The "comb sign" represents engorged vasa recta in the mesentery, a sign of inflammation.
Implications:
- Recognizing these CT findings can expedite the diagnosis of HSP.
- CT imaging can help assess the severity of gastrointestinal involvement and guide management.


