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Related Concept Videos

Alterations in Blood Pressure01:30

Alterations in Blood Pressure

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Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
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Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

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Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
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Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

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Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
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Blood Pressure01:30

Blood Pressure

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Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
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Blood Pressure01:24

Blood Pressure

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The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
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Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
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Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

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Postprandial hypotension: a systematic review.

Laurence G Trahair1, Michael Horowitz1, Karen L Jones1

  • 1Discipline of Medicine, University of Adelaide, Adelaide, Australia; NHMRC Center of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia.

Journal of the American Medical Directors Association
|March 18, 2014
PubMed
Summary
This summary is machine-generated.

Postprandial hypotension (PPH) is common in older adults, causing significant morbidity. Further research into its poorly understood pathophysiology is crucial for effective management.

Keywords:
PPHPostprandial hypotensionblood pressurefaintingfalls

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Area of Science:

  • Gerontology
  • Cardiovascular Medicine
  • Gastroenterology

Background:

  • Postprandial hypotension (PPH) is a significant clinical issue often overlooked.
  • It disproportionately affects the elderly population, contributing to substantial morbidity.

Purpose of the Study:

  • To systematically review the epidemiology, pathophysiology, and management of PPH.
  • To highlight the need for further research into PPH mechanisms and treatment.

Main Methods:

  • A comprehensive systematic literature search was performed across major scientific databases (PubMed, Embase, Cochrane Library, Web of Knowledge).
  • Studies were screened for relevance to PPH epidemiology, pathophysiology, and management.
  • 167 eligible full-text papers were selected from an initial retrieval of 417 papers.

Main Results:

  • Postprandial hypotension (PPH) is a prevalent condition in older individuals.
  • It is associated with considerable morbidity.
  • The pathophysiology involves complex factors including autonomic dysfunction and gastrointestinal processes.

Conclusions:

  • PPH is a common and serious condition in the elderly.
  • Current understanding of PPH pathophysiology is incomplete, involving factors like impaired autonomic function, peptide release, nutrient delivery, and splanchnic blood pooling.
  • Existing management strategies for PPH are suboptimal, necessitating prioritized research for improved therapeutic targeting.