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Load cycling enhances bioactivity at the resin-dentin interface.

Manuel Toledano1, Fátima S Aguilera1, Salvatore Sauro2

  • 1University of Granada, Faculty of Dentistry, Dental Materials Section, Colegio Máximo de Cartuja s/n, 18071 Granada, Spain.

Dental Materials : Official Publication of the Academy of Dental Materials
|March 18, 2014
PubMed
Summary

Mechanical loading enhances mineralization at the resin-dentin interface, improving bonding. This study found that mechanical loading promoted bioactivity and increased mineral content in dental adhesives after 3 weeks.

Keywords:
AFMAdhesiveLongevityRamanRemineralization

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Area of Science:

  • Biomaterials Science
  • Dental Materials Science
  • Adhesive Dentistry

Background:

  • The resin-dentin interface is crucial for the longevity of dental restorations.
  • Understanding factors that promote bioactivity and remineralization at this interface is essential for improving adhesive dentistry outcomes.

Purpose of the Study:

  • To investigate whether mechanical loading influences bioactivity at the resin-dentin interface.
  • To compare the effects of mechanical loading on three different dentin adhesive systems: etch-and-rinse with phosphoric acid (PA+SB), etch-and-rinse with EDTA (EDTA+SB), and self-etch (SEB).

Main Methods:

  • Dentin surfaces were treated with PA+SB, EDTA+SB, or SEB adhesives.
  • Bonded interfaces were stored in simulated body fluid for 24 hours or 3 weeks.
  • Mechanical loading was applied to half of the specimens, and remineralization was assessed using AFM, nano-indentation, Raman spectroscopy, CLSM, and Masson's trichrome staining.

Main Results:

  • Mechanical loading over 3 weeks increased mechanical properties at the resin-dentin interface.
  • Cluster analysis showed a higher mineral-matrix ratio in Single Bond (SB)-loaded specimens.
  • Confocal laser scanning microscopy (CLSM) revealed no micropermeability or nanoleakage in EDTA+SB and SEB specimens after loading.

Conclusions:

  • In vitro mechanical loading effectively promotes mineralization within the resin-dentin interfaces.
  • This effect was observed at both 24-hour and 3-week storage periods.
  • Mechanical loading appears to enhance the stability and bioactivity of the resin-dentin interface, particularly with EDTA-based and self-etch adhesives.