Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Epithelioid sarcoma--immunohistochemical and ultrastructural study].

Z M Ji1, C L Ren, Y Tau

  • 1Zhongshan University of Medical Sciences, Guangzhou.

Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
|March 1, 1988
PubMed
Summary

Immunohistochemistry and electron microscopy aid in diagnosing epithelioid sarcoma. These techniques help differentiate it from other tumors, improving diagnostic accuracy for challenging cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Mitochondrial complexⅠdeficiency nuclear type 20 caused by compound heterozygous ACAD9 mutations: a case report].

Zhonghua xin xue guan bing za zhi·2026
Same author

[Diagnostic value of ultrasonic endoscopy in colorectal endometriosis].

Zhonghua fu chan ke za zhi·2025
Same author

[Expert consensus on the treatment timing calender of congenital ear malformation with multiple malformations].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2025
Same author

Heterogeneity of CFTR modulator-induced sweat chloride concentrations in people with cystic fibrosis.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2024
Same author

[Impact of different diagnostic criteria for assessing mild micro-hepatic encephalopathy in liver cirrhosis: an analysis based on a prospective, multicenter, real-world study].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2023
Same author

Willingness of people with cystic fibrosis receiving elexacaftor/tezacaftor/ivacaftor (ETI) to participate in randomized modulator and inhaled antimicrobial clinical trials.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2023

Area of Science:

  • Oncology
  • Pathology
  • Cell Biology

Context:

  • Epithelioid sarcoma is a rare soft tissue tumor.
  • Accurate diagnosis is crucial for appropriate patient management.
  • Differential diagnosis can be challenging with conventional histology.

Purpose:

  • To evaluate the utility of immunohistochemistry and electron microscopy in diagnosing epithelioid sarcoma.
  • To differentiate epithelioid sarcoma from other sarcomas and metastatic carcinoma.
  • To investigate the potential cellular origin of epithelioid sarcoma.

Summary:

  • Five epithelioid sarcoma cases were analyzed using immunohistochemistry (cytokeratin, carcinoembryonic antigen) and electron microscopy.
  • Immunohistochemistry showed variable cytokeratin positivity, aiding differentiation from malignant fibrous histiocytoma and rhabdomyosarcoma.

Related Experiment Videos

  • Electron microscopy revealed distinct cell features, ruling out carcinoma and supporting the diagnosis in a misdiagnosed case.

    • Impact:

    • Immunohistochemistry and electron microscopy are valuable tools for diagnosing difficult epithelioid sarcoma cases.
    • These methods enhance diagnostic specificity and can prevent misdiagnosis.
    • Findings suggest epithelioid sarcoma cells may originate from undifferentiated mesenchymal cells.