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Updated: May 2, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
[Epidemiologic warnings from studies on alcohol use disorders]
1Service de psychiatrie de l'adulte et du sujet âgé, hôpital Corentin-Celton, groupe hospitalier - hôpitaux universitaires Paris-Ouest, Assistance publique-Hôpitaux de Paris (AP-HP), 4, parvis Corentin-Celton, 92130 Issy-les-Moulineaux, France; Sorbonne Paris-Cité, université Paris Descartes, 75006 Paris, France; Inserm, U894, centre de psychiatrie et neurosciences, 75014 Paris, France.
Alcohol use remains high globally, causing significant disease and social costs. A vast majority of individuals with alcohol use disorders, particularly in Europe, do not receive necessary treatment, highlighting a critical gap in healthcare.
Area of Science:
- Public Health
- Epidemiology
- Addiction Medicine
Context:
- Alcohol consumption is highest in the developed Northern Hemisphere, with European adult per capita consumption at 12.5 liters in 2009.
- Harmful alcohol use is a leading global health risk, directly causing over 30 diseases and contributing to over 60 others.
- In France, 4-5% of adults are alcohol-dependent, and 5 million are excessive drinkers, indicating significant public health challenges.
Purpose:
- To highlight the substantial burden of alcohol use disorders (AUDs) on global health and societal well-being.
- To identify the significant treatment gap for alcohol abuse and dependence worldwide, particularly in Europe.
- To advocate for healthcare system adaptation to address the unmet needs of individuals with AUDs.
Summary:
- Alcohol consumption contributes to millions of deaths annually and a significant global burden of disease and injury.
- Psychosocial consequences of alcohol, including violence and lost productivity, result in substantial economic costs, estimated at €155.8 billion yearly in Europe.
- A median of 78.1% of alcohol use disorder cases remain untreated globally, with Europe showing a 92% treatment gap.
Impact:
- Alcohol-attributable deaths and disability-adjusted life years (DALYs) represent a major public health concern.
- The societal costs of alcohol abuse extend beyond the individual, affecting families, workplaces, and healthcare systems.
- Addressing the treatment gap for alcohol use disorders is crucial for improving health outcomes and reducing societal burdens.
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